Shaking with Laughter is a newly established charitable 501(c)3 in Cleveland, with the mission to fund research for a cure for Parkinson's Disease.

Founded by Karen Jaffe, a prominent Cleveland OB/GYN, and her husband Marc, a well-known comedian and writer, after Karen was diagnosed with Parkinson's, Shaking with Laughter will present events that include humor in an effort to raise funds for research.

Parkinson's disease is a chronic, degenerative neurological disorder whose symptoms can progress from mild tremors to complete physical incapacitation. In the United States 60,000 new cases of PD will be diagnosed this year alone. While the average age of onset is 60, an estimated five to 10 percent of people with PD experience onset at age 40 or younger.

All of the proceeds from this year's Shaking With Laughter events will be donated to the Michael J. Fox Foundation for Parkinson's Research. The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda all while maintaining a lean organization with less than 3% of their costs going to administration.

On Saturday September 22nd Shaking With Laughter presents Grammy winning blues guitarist Keb’ Mo’ and the hysterical Jake Johannsen in a gala evening of comedy and music at the beautiful Ohio Theater at Playhouse Square in Cleveland. Tickets are available at shakingwithlaughter.org and playhouse.org.